Risk factors to predict severe postoperative pancreatic fistula following gastrectomy for gastric cancer

Table 2 Comparison of clinicopathologic factors and International Study Group on Pancreatic Fistula classification in patients with severe postoperative pancreatic fistula between short and long duration of intensive treatments n (%)

Variables		Intensive treatment periods for POPF		1P value
		< 20 d	20 d ≤
Sex	Male	10 (83)	20 (87)
	Female	2 (17)	3 (13)	0.827
Age (yr)	< 65	5 (42)	7 (30)
	65 ≤	7 (58)	16 (70)	0.772
BMI (kg/m2)	< 21	5 (42)	6 (27)
	21 ≤	7 (58)	16 (73)	0.636
pT-stage	T1 T2	3 (25)	3 (13)
	T3 T4	9 (75)	20 (87)	0.391
pN-stage	N1 N2	5 (42)	16 (70)
	N3	7 (58)	7 (30)	0.217
pStage	III	4 (33)	5 (22)
	III IV	8 (67)	18 (78)	0.736
Splenectomy	Presence	7 (58)	14 (61)
	Absence	5 (42)	9 (39)	0.827
Pancreatico-splenectomy	Presence	2 (17)	10 (43)
	Absence	10 (83)	13 (57)	0.149
Lymphadenectomy	< D2	2 (17)	6 (26)
	D2 ≤	10 (83)	17 (74)	0.685
Resection status	R0	5 (42)	5 (22)
	R1	4 (33)	11 (48)
	R2	3 (25)	7 (30)	0.728
Blood loss (g)	< 1000	3 (25)	9 (39)
	1000 ≤	9 (75)	14 (61)	0.476
Operation time (min)	< 330	6 (50)	11 (48)
	330 ≤	6 (50)	12 (52)	0.815
Preoperative Hb (g/dL)	< 10	5 (42)	3 (13)
	10 ≤	7 (58)	20 (87)	0.091
Preoperative Alb (g/dL)	≤ 3.5	3 (30)	6 (29)
	3.5 <	7 (70)	15 (71)	1.000
2Lymphocyte counts (/mm3)	< 850	5 (42)	18 (78)
	850 ≤	7 (58)	5 (22)	0.073
ISGPF classification	grade B	9 (75)	8 (35)
	grade C	3 (25)	15 (65)	0.0353

¹P values were derived from the χ² or Fisher's exact test and were considered significant at < 0.05.

²Lymphocyte counts at the diagnosis of POPF;

³Significant values. ISGPF: International Study Group on Pancreatic Fistula; POPF: Postoperative pancreatic fistula; BMI: Body mass index.