Endoscopic papillary large balloon dilation for the removal of bile duct stones

Table 9 Comparison among endoscopic sphincterotomy, endoscopic papillary balloon dilation, and endoscopic papillary balloon dilation with endoscopic sphincterotomy n (%)

	EST1	EPBD1	No. of studies	EPLBD with EST	No. of studies	P value
No. of procedures	890	878	15	2511	30
Mean age, range, yr	47-71	49-75	15	40-82	29
Mean stone size, range, mm	7.3-16.9	7-15.6	15	5-45	25
Initial success	322 (80.9)	285 (73.5)	7	1745 (84.0)	24	< 0.001
Use of EML	121 (13.3)	162 (19.6)	13	353 (14.1)	30	< 0.001
Overall success	776 (95.3)	733 (90.1)	13	2407 (96.5)	30	< 0.001
Overall adverse events	113 (12.7)	106 (12.1)	15	209(8.3)	30	< 0.001
Pancreatitis	36 (4.3)	71 (8.6)	14	61 (2.4)	30	< 0.001
Bleeding	33 (4.8)	1 (0.1)	12	91 (3.6)	30	< 0.001
Perforation	3 (0.5)	2 (0.3)	9	15 (0.6)	30	0.941
AE-related death	2 (0.3)	4 (0.7)	7	6 (0.24)	30	0.152

¹Results of a meta-analysis by Weinberg et al[18]. EST: Endoscopic sphincterotomy; EPBD: Endoscopic papillary balloon dilation; EPLBD: Endoscopic papillary large balloon dilation; EML: Endoscopic mechanical lithotripsy.