Endoscopic papillary large balloon dilation for the removal of bile duct stones

Table 8 Comparison of adverse events among endoscopic papillary large balloon dilation with large, limited and without endoscopic sphincterotomy n (%)

	EPLBD with large EST	EPLBD with limited EST	EPLBD without EST	P value
No. of procedures	756	946	413
Overall adverse event	65 (8.6)	71 (7.5)	29 (7.0)	0.568
Pancreatitis	18 (2.4)	29 (3.1)	16 (3.9)	0.349
Bleeding	31 (4.1)	12 (1.3)	8 (1.9)	0.0011
Perforation	3 (0.4)	5 (0.5)	2 (0.5)	1.000
Other adverse events	13 (1.7)	25 (2.6)	3 (0.7)	0.054
AE-related surgery	2 (0.3)	2 (0.2)	0 (0.0)	0.832
AE-related death	2 (0.3)	0 (0.0)	0 (0.0)	0.166

¹EPLBD with large EST vs EPLBD with limited EST, P < 0.001; EPLBD with large EST vs EPLBD without EST, P = 0.049; EPLBD with limited EST vs EPLBD without EST, P = 0.35. EPLBD: Endoscopic papillary large balloon dilation; EST: Endoscopic sphincterotomy; AE: Adverse event.