Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma

Figure 5 Detection of apoptotic cells in xenograft tumor tissue by the terminal deoxynucleotidyl transferase dUTP nick end labeling assay. A: Control group; B: SIN group; C: 5-FU group; D: Combined group; SIN and 5-FU induced significant apoptosis of esophageal carcinoma cells in vivo compared with the saline control group (P < 0.05), and the apoptotic rate of the combination treatment group was more significant than that of the SIN alone and 5-FU alone groups. SIN: Sinomenine; 5-FU: 5-Fluorouracil.