Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma

Figure 1 The individual and combined effects of sinomenine and 5-Fluorouracil on the proliferation of esophageal carcinoma cells. The proliferation of Esophageal carcinoma (Eca-109) cells was inhibited by SIN and 5-FU in a dose dependent manner (P < 0.05). SIN and 5-FU had significant synergistic effects on inhibiting the proliferation of Eca-109 cells especially at lower concentrations. SIN: Sinomenine; 5-FU: 5-Fluorouracil.