Role of the advanced glycation end products receptor in Crohn’s disease inflammation

Figure 3 Receptor for the advanced glycation end products staining in Crohn’s disease and healthy mucosa lamina propria. A: Many lamina propria mononuclear cells proved receptor for the advanced glycation end products (RAGE)-positive (the brown cells) in a representative case of Crohn’s disease affected areas; B: A cluster of RAGE-positive lamina propria mononuclear cells next to an ulceration (red arrow) in a representative case of Crohn’s disease affected area showing a cytosolic distribution; C: A representative case of control mucosa is shown, with weak staining of a few lamina propria mononuclear cells (black arrow) (RAGE immunoperoxidase-hematoxylin; original magnification, × 200).