Association of visceral obesity and early colorectal neoplasia

Table 3 Body measure index, adipose tissue area and the risk of colorectal cancer vs colorectal adenoma

	Univariate		Multivariate 11		Multivariate 22
	OR (95%CI)	P value	OR (95%CI)	P value	OR (95%CI)	P value
BMI
Quartile I	1	0.9373	1	0.8873
Quartile II	0.87 (0.51-1.48)	0.600	0.86 (0.50-1.48)	0.595
Quartile III	0.96 (0.58-1.58)	0.875	0.96 (0.58-1.58)	0.857
Quartile IV	0.95 (0.58-1.55)	0.824	0.93 (0.57-1.53)	0.777
VAT
Quartile I	1	0.0323	1	0.0243	1	0.0283
Quartile II	0.74 (0.45-1.21)	0.227	0.74 (0.45-1.20)	0.224	0.70 (0.42-1.18)	0.182
Quartile III	0.71 (0.43-1.17)	0.182	0.68 (0.41-1.13)	0.141	0.65 (0.38-1.12)	0.118
Quartile IV	0.57 (0.35-0.94)	0.028	0.56 (0.34-0.92)	0.023	0.53 (0.31-0.92)	0.024
SAT
Quartile I	1	0.5503	1	0.5563	1	0.7293
Quartile II	0.90 (0.55-1.49)	0.686	0.91 (0.55-1.50)	0.697	1.08 (0.63-1.83)	0.786
Quartile III	1.03 (0.62-1.71)	0.898	1.02 (0.62-1.70)	0.933	1.26 (0.73-2.17)	0.407
Quartile IV	0.82 (0.49-1.35)	0.427	0.82 (0.50-1.36)	0.443	1.09 (0.62-1.91)	0.362

¹Multivariate model 1 was adjusted for current smoking status, and alcohol consumption;

²Multivariate model 2 was adjusted for subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT), in addition. Since body mass index (BMI) showed co-linearity to adipose tissue amount, it was not included in the analysis;

³P value for test of trend of odds.