Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma

Table 2 Inhibitory effect of sinomenine and 5-Fluorouracil on esophageal carcinoma tumor weight in nude mice

Group	n	Weight (g)	Inhibition rate (%)
SIN	6	0.218 (0.061)bd	63.10
5-FU	6	0.225 (0.088)bd	61.97
SIN + 5-FU	6	0.098 (0.066)d	83.38
Control	6	0.593 (0.070)

Data presented as mean (SD) and are expressed as inhibition rate (%) = (1 - mean of tumor weight of tests/mean of tumor weight of control) × 100%. There were 6 mice per group.

^bP < 0.05, significantly different from SIN + 5-FU group;

^dP < 0.05, significantly different from control group. SIN: Sinomenine; 5-FU: 5-Fluorouracil.