Cooperative inhibitory effect of sinomenine combined with 5-fluorouracil on esophageal carcinoma

Table 1 Inhibitory effect of sinomenine and 5-Fluorouracil on esophageal carcinoma tumor volume in nude mice

Group	n	Volume (mm3)	Inhibition rate (%)
SIN	6	161.94 (40.96)bd	64.68
5-FU	6	129.82 (16.39)bd	71.68
SIN + 5-FU	6	40.27 (5.55)d	91.22
Control	6	540.20 (66.04)

Data presented as mean (SD) and are expressed as inhibition rate (%) = (1 - mean of tumor volume of tests/mean of tumor volume of control) × 100%. There were 6 mice per group.

^bP < 0.05, significantly different from SIN + 5-FU group;

^dP < 0.05, significantly different from control group. SIN: Sinomenine; 5-FU: 5-Fluorouracil.