Small cell carcinoma of the liver and biliary tract without jaundice

Figure 3 Tumor consisted of tightly packed nests and diffuse, irregularly shaped sheets of cells with necrotic areas. A: The tumor cells were of small-to-intermediate size with hyperchromatic, round-to-oval nuclei and scanty, poorly defined cytoplasm (HE, × 100); B: The nuclear chromatin was finely granular, and nucleoli were absent or inconspicuous. Cell borders were rarely seen, and nuclear molding was common (HE, × 400).