Shugan-decoction relieves visceral hyperalgesia and reduces TRPV1 and SP colon expression

Figure 1 Reductions in the expressions of substance P and transient receptor potential vanilloid 1 protein by water avoidance stress in the colon are relieved by SGJGD treatment. A-F: Substance P protein; G-L: Transient receptor potential vanilloid 1. IHC-detected colon tissues (× 200) from: untreated normal group (A, G); untreated model group (B, H); high-dose Shugan-decoction (SGD) model group (C, I); mid-dose SGD model group (D, J); low-dose SGD model group (E, K); dicetel control model group (F, L).