Exocrine pancreatic insufficiency in adults: A shared position statement of the Italian association for the study of the pancreas

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Nov 28, 2013 (publication date) through Dec 17, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 28, 2013; 19(44): 7930-7946
Published online Nov 28, 2013. doi: 10.3748/wjg.v19.i44.7930

Table 2 Pathogenesis of maldigestion

Mechanism	Explanation
Decreased pancreatic production	Lack of functional tissue or decreased endogenous neurohormonal stimulation
Decrease in delivery	Pancreatic duct obstruction
Decreased activation	Low duodenal pH
Premature enzymatic degradation	Decreased contact time due to increased motility, impaired interaction with chyme and biliary salts, and intestinal bacterial overgrowth

Citation: Pezzilli R, Andriulli A, Bassi C, Balzano G, Cantore M, Fave GD, Falconi M, Group LFTEPIC(. Exocrine pancreatic insufficiency in adults: A shared position statement of the Italian association for the study of the pancreas. World J Gastroenterol 2013; 19(44): 7930-7946
URL: https://www.wjgnet.com/1007-9327/full/v19/i44/7930.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i44.7930