Events associated with apoptotic effect of p-Coumaric acid in HCT-15 colon cancer cells

Figure 1 Antiproliferative effect, colony inhibitory of p-Coumaric acid against colon cancer cells. A: Both human colorectal carcinoma (HCT-15) and HT-29 cells grown in 96-well plate were treated with various concentration of p-Coumaric acid (0-10000 μmol/L) diluted in the media for 48 h. The mean of the percentage cell viability (% of control) along with their standard error is indicated; B: After various incubation periods of p-Coumaric acid treatment, colonies formed were stained with 0.5% crystal violet and counted, and percentage of survival was calculated by normalizing the values. Data reported as the mean ± SE from three different observations. Mean differences are significant at 12, 24 and 48 h.