8-bromo-7-methoxychrysin inhibits properties of liver cancer stem cells via downregulation of β-catenin

Figure 4 8-bromo-7-methoxychrysin eliminated liver cancer stem cells derived from MHCC97 cell line in vivo. Effects of 8-bromo-7-methoxychrysin (BrMC) on growth of primary and secondary tumor xenografts derived from liver cancer stem cells (LCSCs) (A and B, mean ± SD, n = 12). ^aP < 0.05 vs refined olive oil treatment model, ^cP < 0.05 vs treatment with 12.5 mg/kg BrMC. Immunohistochemical analysis of CD44 and CD133 in LCSC-derived tumors before and after BrMC treatment (C and D).