Amelioration of carbon tetrachloride-induced cirrhosis and portal hypertension in rat using adenoviral gene transfer of Akt

Table 3 Portal vein pressure, mean arterial pressure and heart rate in each experiment group at the end of the treatment

Group	n	PVP (mmHg)	MAP (mmHg)	HR
Normal	5	8.96 ± 1.46	83.5 ± 9.8	323 ± 73
Cirrhosis	20
Untreated	5	16.01 ± 1.32a	79.6 ± 14.2	339 ± 89
Saline	5	15.87 ± 1.40a	80.1 ± 11.5	282 ± 101
EGFP	5	15.65 ± 1.18a	82.9 ± 12.9	319 ± 78
Akt	5	9.23 ± 1.51ceg	88.5 ± 17.6	289 ± 96

^aP < 0. 05 (vs Normal control);

^cP < 0. 05 (vs Untreated group);

^eP < 0. 05 (vs Saline group);

^gP < 0. 05 [vs enhanced green fluorescent protein (EGFP) group]. No difference was detected among Untreated, Saline and EGFP groups. PVP: Portal vein pressure; MAP: Mean arterial pressure; HR: Heart rate.