Amelioration of carbon tetrachloride-induced cirrhosis and portal hypertension in rat using adenoviral gene transfer of Akt

Table 2 Liver function parameter in each experiment group in each experimental group

Group	n	ALT (U/L)	AST (U/L)	ALB (g/L)	Hyp (μg/g)
Normal	5	23.5 ± 6.3	109.3 ± 6.1	33.1 ± 2.6	180.5 ± 12.5
Cirrhosis	20
Untreated	5	277.6 ± 25.8a	380.5 ± 16.9a	22.7 ± 3.5a	375.2 ± 17.3a
Saline	5	290.7 ± 22.9a	368.9 ± 23.8a	24.7 ± 3.7a	393.8 ± 22.3a
EGFP	5	285.9 ± 27.3a	374.4 ± 26.7a	23.9 ± 2.9a	388.5 ± 9.8a
Akt	5	126.4 ± 5.8aceg	202.5 ± 9.5aceg	30.7 ± 4.8aceg	245.9 ± 15.6aceg

^aP < 0.05 (vs Normal control);

^cP < 0.05 (vs Untreated group);

^eP < 0.05 (vs Saline group);

^gP < 0.05 [vs enhanced green fluorescent protein (EGFP) group]. No difference was detected among Untreated, Saline and EGFP groups. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALB: Albumin; Hyp: Hepatic hydroxyproline.