Amelioration of carbon tetrachloride-induced cirrhosis and portal hypertension in rat using adenoviral gene transfer of Akt

Table 1 Portal vein diameter, peak velocity of blood flow, congestion index and blood flow in each experimental group

Group	n	D (mm)	V (cm/s)	CI	Q (mL/min)
Normal	5	1.13 ± 0.24	12.67 ± 0.64	0.0010 ± 0.0003	4.56 ± 1.86
Cirrhosis	20
Untreated	5	1.81 ± 0.19a	10.13 ± 0.68a	0.0021 ± 0.0007a	9.69 ± 2.58a
Saline	5	1.83 ± 0.29a	10.06 ± 0.72a	0.0024 ± 0.0008a	9.32 ± 2.83a
EGFP	5	1.82 ± 0.27a	9.98 ± 0.77a	0.0020 ± 0.0006a	8.97 ± 2.45a
Akt	5	1.28 ± 0.32ceg	11.39 ± 0.63ceg	0.0013 ± 0.0004ceg	5.11 ± 2.30ceg

^aP < 0.05 (vs Normal control);

^cP < 0.05 (vs Untreated group);

^eP < 0.05 (vs Saline group);

^gP < 0.05 [vs enhanced green fluorescent protein (EGFP) group]. No difference was detected among Untreated, Saline and EGFP groups. D: Diameter; V: Peak velocity of blood flow; CI: Congestion index; Q: Blood flow.