Screening of SLC25A13 mutation in the Thai population

Table 1 Number of individuals with SLC25A13 mutations and carrier prevalence in the Thai population according to geographical distribution

Region	Mutation [I] (c.851_854delGTAT)	Mutation XIX (g.IVS16ins3kb)	p.Met1?	Total carriers (p.Met1? not included)	Total carriers (p.Met1? included)
Bangkok (n = 142)	2 (1/71)1	2 (1/71)	5 (1/28)1	4 (1/36)	8 (1/18)1
Central (n = 387)	0	3 (1/129)	17 (1/23)	3 (1/129)	20 (1/19)
Northeastern (n = 498)	4 (1/125)	0	27 (1/18)	4 (1/125)	31 (1/16)
Northern (n = 291)	1 (1/291)	3 (1/97)	21 (1/14)	4 (1/74)	25 (1/12)
Southern (n = 219)	1 (1/219)	1 (1/219)	15 (1/15)	2 (1/110)	17 (1/13)
Total (n = 1537)	8 (1/192)	9 (1/171)	85 (1/18)	17 (1/90)	101 (1/15)
P value2	0.18	0.067	0.366	NA	0.413

¹One individual was found with compound heterozygote of Mutation [I] (c.851_854 delGTAT) and p.Met1?;

²Statistical analysis using Fischer’s Exact test giving P value for comparison of the carrier prevalence identified across the regions. NA: Not available.