Prognostic factors in non-malignant and non-cirrhotic patients with portal cavernoma: An 8-year retrospective single-center study

Table 4 Univariate analysis of baseline variables predicting overall survival

Variables	HR	95%CI	Pvalue
Sex (female/male)	0.559	0.108-2.883	0.487
Age at admission	1.032	0.984-1.083	0.194
Age at first diagnosis ( ≤ 18 yr/> 18 yr)	0.840	0.187-3.772	0.820
History of portal cavernoma	0.989	0.878-1.114	0.857
Varices (yes/no)	0.428	0.083-2.213	0.311
Variceal bleeding (yes/no)	2.450	0.475-12.653	0.285
Abdominal distension (yes/no)	2.253	0.435-11.657	0.333
Abdominal pain (yes/no)	2.010	0.450-8.989	0.361
Ascites (yes/no)	15.066	1.811-125.337	0.012
Hydrothorax (yes/no)	6.638	1.452-30.346	0.015
RBC	0.681	0.288-1.614	0.383
Hb	0.987	0.964-1.011	0.302
PLT	1.000	0.997-1.003	0.900
WBC	1.099	1.040-1.162	0.001
PT	1.083	0.751-1.562	0.668
INR	5.253	0.057-480.003	0.471
ALT	0.970	0.915-1.029	0.312
AST	0.966	0.905-1.032	0.305
AST/ALT	2.328	0.891-6.083	0.085
ALP	1.003	0.993-1.013	0.558
GGT	1.003	0.989-1.017	0.684
ALB	0.932	0.795-1.094	0.392
TBIL	1.028	0.969-1.091	0.358
DBIL	1.036	0.941-1.140	0.470
Serum Cr	1.007	0.971-1.045	0.704
Serum Na	0.764	0.635-0.918	0.004
Child-Pugh score	1.573	0.976-2.535	0.063
Child-Pugh class (class A/class B and C)	0.083	0.009-0.763	0.028
MELD score	1.067	0.899-1.267	0.459
TIPS insertion (failure/success)	0.677	0.095-4.806	0.696
Main portal vein (patency/obstruction)	0.042	0.0001-1720.16	0.558
Main portal vein (no fibrotic cord/fibrotic cord)	0.798	0.155-4.113	0.787
Right portal vein (patency/obstruction)	2.269	0.507-10.151	0.284
Left portal vein (patency/obstruction)	1.639	0.318-8.455	0.555
Splenic vein (patency/obstruction and splenectomy)	0.533	0.103-2.766	0.454
Superior mesenteric vein (patency/obstruction)	0.159	0.019-1.330	0.090

RBC: Red blood cell; Hb: Hemoglobin; WBC: White blood cell; PLT: Platelets; PT: Prothrombin time; INR: International normalized ratio; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: γ-glutamyl transferase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin; MELD: Model for end-stage liver disease; TIPS: Transjugular intrahepatic portosystemic shunt.