Prognostic factors in non-malignant and non-cirrhotic patients with portal cavernoma: An 8-year retrospective single-center study

doi:10.3748/wjg.v19.i42.7447

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 14, 2013; 19(42): 7447-7454
Published online Nov 14, 2013. doi: 10.3748/wjg.v19.i42.7447

Table 2 Clinical profile in patients with and without variceal bleeding

Variables	Variceal bleeding (n= 29)	No variceal bleeding (n= 35)	Pvalue
Age at admission (yr)	25.41 ± 2.74	37.54 ± 2.56	0.002
Sex (female/male)	14/15	12/23	0.257
History of portal cavernoma (yr)	5.89 ± 1.44	1.86 ± 0.66	0.009
Abdominal distension (yes/no)	11/18	26/9	0.003
Abdominal pain (yes/no)	3/26	23/12	< 0.001
Ascites (yes/no)	8/21	12/23	0.565
Hydrothorax (yes/no)	4/25	6/29	0.713
Jaundice (yes/no)	2/27	2/33	0.846
RBC (10¹²/L)	3.36 ± 0.12	4.44 ± 0.12	< 0.001
Hb (g/L)	87.21 ± 4.60	122.03 ± 4.86	< 0.001
WBC (10⁹/L)	7.47 ± 1.82	8.65 ± 1.16	0.574
PLT (10⁹/L)	317.07 ± 50.27	283.53 ± 45.84	0.624
PT (s)	14.08 ± 0.35	14.18 ± 0.34	0.838
INR	1.15 ± 0.03	1.15 ± 0.03	0.946
ALT (U/L )	26.38 ± 4.87	32.94 ± 4.51	0.327
AST (U/L )	28.85 ± 4.28	30.93 ± 3.33	0.388
AST/ALT	1.23 ± 0.08	1.21 ± 0.11	0.874
ALP (U/L )	115.98 ± 13.43	99.94 ± 8.57	0.302
GGT (U/L )	31.69 ± 8.60	49.00 ± 8.12	0.150
ALB (g/L )	37.23 ± 0.79	39.09 ± 0.82	0.111
TBIL (μmol/L)	15.54 ± 2.13	16.48 ± 1.66	0.724
DBIL (μmol/L)	7.07 ± 1.54	7.43 ± 0.98	0.838
Serum Cr (μmol/L)	70.17 ± 3.88	71.06 ± 3.26	0.860
Serum Na (mmol/L)	139.26 ± 0.55	139.77 ± 0.70	0.577
Child-Pugh class (A/B/C)	23/5/1	28/7/0	0.529
Child-Pugh score	5.69 ± 0.21	5.71 ± 0.18	0.928
MELD score	3.93 ± 0.88	4.51 ± 0.65	0.593
Main portal vein (fibrotic cord/complete obstruction/partial obstruction/patency)	27/0/1/1	15/12/3/4	< 0.001
Right portal vein (obstruction/patency)	19/10	30/5	0.058
Left portal vein (obstruction/patency)	21/8	30/5	0.188
Splenic vein (obstruction and splenectomy/patency)	14/15	25/10	0.059
Superior mesenteric vein (obstruction/patency)	11/18	23/12	0.027

Data are expressed as quantitative data as frequency or mean ± SE. RBC: Red blood cell; Hb: Hemoglobin; WBC: White blood cell; PLT: Platelets; PT: Prothrombin time; INR: International normalized ratio; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; ALP: Alkaline phosphatase; GGT: γ-glutamyl transferase; ALB: Albumin; TBIL: Total bilirubin; DBIL: Direct bilirubin; MELD: Model for end-stage liver disease.

Citation: Qi XS, Bai M, He CY, Yin ZX, Guo WG, Niu J, Wu FF, Han GH. Prognostic factors in non-malignant and non-cirrhotic patients with portal cavernoma: An 8-year retrospective single-center study. World J Gastroenterol 2013; 19(42): 7447-7454
URL: https://www.wjgnet.com/1007-9327/full/v19/i42/7447.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i42.7447