Differentiation between dysplastic nodule and early-stage hepatocellular carcinoma: The utility of conventional MR imaging

Table 3 Comparison of magnetic resonance features between dysplastic nodule and well-differentiated hepatocellular carcinoma

	DN (n = 14)	wHCC		P value
		w1 (n = 40)	w2 (n = 19)	DN vs wHCC	DN vs w1	w1 vs w2
In-phase T1WI				0.469	0.405	0.074
Hyperintense	8	29	8
Isointense	4	5	4
Hypointense	2	6	7
Opposed-phase T1WI				0.661	0.565	0.007
Hyperintense	8	25	4
Isointense	3	4	6
Hypointense	3	11	9
Fatty metamorphosis				0.192	0.311	0.450
Positive	0	5	4
Negative	14	35	15
T2WI				0.006	0.020	0.109
Hyperintense	1	14	12
Isointense	6	5	2
Hypointense	7	21	5
Arterial enhancement				0.767	0.753	0.005
Hypervascular	5	12	13
Iso-/hypo-vascular	9	28	6
Late-phase T1WI				0.112	0.286	0.105
Hyperintense	1	5	3
Isointense	12	26	7
Hypointense	1	9	9

T1WI: T1-weighted imaging; T2WI: T2-weighted imaging; DN: Dysplastic nodule; wHCC: Well-differentiated hepatocellular carcinoma; w1: wHCC compatible with Edmondson-Steiner grade I; w2: wHCC compatible with Edmondson-Steiner grade II.