PNPLA3 I148M polymorphism and progressive liver disease

doi:10.3748/wjg.v19.i41.6969

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 7, 2013; 19(41): 6969-6978
Published online Nov 7, 2013. doi: 10.3748/wjg.v19.i41.6969

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Figure 1 Hypothetical mechanism of hepatic fat accumulation associated with the 148 Isoleucine to Methionine protein variant patatin-like phospholipase domain-containing 3 polymorphism. ER: Endoplasmic reticulum; LPA: Lyso-phosphatidic acid; PA: Phosphatidic acid; Tg: Triglycerides; ?: To be confirmed; PNPLA3: Patatin-like phospholipase domain-containing 3.

Citation: Dongiovanni P, Donati B, Fares R, Lombardi R, Mancina RM, Romeo S, Valenti L. PNPLA3 I148M polymorphism and progressive liver disease. World J Gastroenterol 2013; 19(41): 6969-6978
URL: https://www.wjgnet.com/1007-9327/full/v19/i41/6969.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i41.6969