Association between Ras association domain family 1A promoter methylation and hepatocellular carcinoma: A meta-analysis

Table 3 Quality Assessment of Diagnostic Accuracy Studies-2 results of all included studies

Study	Risk of bias				Applicability concerns
	Patient selection	Index test	Reference standard	Flow and timing	Patient selection	Index test	Reference standard
Chan et al[22]	↑	?	↓	↓	↓	?	↓
Chang et al[23]	↑	?	↓	↓	↓	?	↓
Maurizio et al[24]	↑	?	↓	?	↓	?	↓
Mohamed et al[25]	↑	↓	↓	↓	↓	↓	↓
Azab et al[26]	↑	↓	↓	↓	↓	↓	↓
Zhang et al[27]	↑	↓	↓	↓	↓	↓	↓
Huang et al[28]	↑	?	↓	↓	↓	?	↓

↓: Low risk; ↑: High risk; ?: Unclear risk.