Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy

Table 5 Outcomes of cirrhotic patients n (%)

Variables	Cirrhotic Group	Patients without PHT (51 patients)	Patients with PHT (16 patients)	P values
Age
Mean (yr)	54.07 ± 9.43	54.66 ± 10.05	52.18 ± 7.04	NS
< 60 yr	48 (71.6)	35 (68.6)	13 (81.3)	NS
> 60 yr	19 (28.4)	16 (31.4)	3 (18.8)
Sex
Male	52 (77.6)	40 (78.4)	12 (75)	NS
Female	15 (22.4)	11 (21.6)	4 (25)
Median blood loss (mL)	500 (100-2500)	300 (100-2500)	1000 (200-2500)	0.001
< 500 mL	31 (46.3)	26 (51)	5 (31.3)	NS
> 500 mL	36 (53.7)	25 (49)	11 (68.8)
Blood transfusion
Median (unite)	1 (0-4)	1 (0-4)	2 (0-4)	0.020
Number of patients	38 (56.7)	26 (51)	12 (75)
Operative time (h)	5.81 ± 0.87	5.8 ± 0.91	5.68 ± 0.72	NS
Hospital stay (d)	12.97 ± 11.2	14.5 ± 10.2	12.49 ± 11.55	NS
Pancreatic fistula	13 (19.4)	7 (13.7)	6 (37.5)	NS
Grade A	5 (7.5)	3 (5.9)	2 (12.5)	NS
Grade B	3 (4.5)	1 (2)	2 (12.5)
Grade C	5 (7.5)	3 (5.9)	2 (12.5)
Delayed gastric emptying	10 (14.9)	6 (11.8)	4 (25)	NS
Biliary leakage	4 (6)	3 (5.9)	1 (6.3)	NS
Wound infection	10 (14.9)	6 (11.8)	4 (25)	NS
Burst wound	4 (6)	2 (3.9)	2 (12.5)	NS
Internal haemorrhage	4 (6)	3 (5.9)	1 (6.3)	NS
Bleeding gastrojejunostomy	1 (1.5)	0	1 (6.3)	NS
Bleeding pancreaticogastrostomy	1 (1.5)	0	1 (6.3)	NS
Abdominal collection	12 (17.9)	8 (15.7)	4 (25)	NS
Encephalopathy	2 (3)	1 (2)	1 (6.3)	NS
Ascites	7 (10.44)	4 (7.8)	3 (18.8)	NS
Re-exploration	8 (11.9)	4 (7.8)	4 (25)	NS
Hospital mortality	8 (11.9)	4 (7.8)	4 (25)	NS
Liver cell failure	4 (6)	2 (3.9)	2 (12.5)
Sepsis	4 (6)	2 (3.9)	2 (12.5)
Pulmonary embolism	0
Median survival (mo)	19	21	18	NS
1 yr	42	41	46
2 yr	13	15	4
3 yr	8	9	0

NS: Not significant; PHT: Portal hypertension.