Impact of cirrhosis on surgical outcome after pancreaticoduodenectomy

Table 4 Postoperative data n (%)

Variables	Cirrhotic group	Non cirrhotic group	P value
	Group A	Group B
Time to resume oral intake (d)	5.98 ± 5.11	6.08 ± 5.71	NS
Drain removal (d)	11.2 ± 9.89	9.41 ± 6.76	NS
Drain amount (mL)	1106.76 ± 1388.91	676.42 ± 1871.36	NS
Complications
Pancreatic fistula	13 (19.4)	37 (9.9)	0.02
Grade A	5 (7.5)	16 (4.3)
Grade B	3 (4.5)	15 (4)	NS
Grade C	5 (7.5)	6 (1.6)
Delayed gastric emptying	10 (14.9)	41 (10.9)	NS
Biliary leakage	4 (6)	19 (5.1)	NS
Wound infection	10 (14.9)	24 (6.4)	0.02
Burst wound	4 (6)	2 (0.5)	0.0001
Internal haemorrhage	4 (6)	7 (1.9)	0.05
Bleeding gastrojejunostomy	1 (1.5)	12 (3.2)	NS
Bleeding pancreaticogastrostomy	1 (1.5)	6 (1.6)	NS
Abdominal collection	12 (17.9)	40 (10.7)	NS
Encephalopathy	2 (3)	0	0.001
Ascites	7 (10.44)	0	0.0001
Re-exploration	8 (11.9)	27 (7.2)	NS
Postoperative albumin (gm%)	2.81 ± 0.56	2.97 ± 0.43	0.01
Postoperative bilirubin (mg%)	4.54 ± 5.1	3.54 ± 3.89	NS
Postoperative SGPT (IU/L)	113.08 ± 50.1	58.35 ± 82.1	0.0001
Hospital mortality	8 (11.9)	6 (1.6)	0.0001
Liver cell failure	4 (6)	0
Sepsis	4 (6)	4 (1)
Pulmonary embolism	0	2 (0.5%)
Postoperative stay (d)	12.97 ± 11.2	10.71 ± 7.41	0.03
Median survival (mo)	19	24	0.009
1 yr	42	59
2 yr	13	29
3 yr	8	19

NS: Not significant.