Curcumin cytotoxicity is enhanced by PTEN disruption in colorectal cancer cells

doi:10.3748/wjg.v19.i40.6814

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Oct 28, 2013 (publication date) through Jan 9, 2025

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2013; 19(40): 6814-6824
Published online Oct 28, 2013. doi: 10.3748/wjg.v19.i40.6814

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Figure 2 Curcumin shows enhanced cytotoxicity toward PTEN-deficient cells. A-E: Cytotoxic effects of irinotecan (CPT-11), 5-fluorouracil (5-FU), dihydroartemisinin (DHA), oxaliplatin (OXA) and curcumin (Cur) on cell viability of HCT116 phosphatase and tensin homolog deleted on chromosome 10 (PTEN)^+/+ and PTEN^-/- cells were determined using the MTT assay; F: Cytotoxic effects of curcumin (Cur) on HCT116 p53^+/+ and p53^-/- cells ( ^bP < 0.01 vs control group).

Citation: Chen L, Li WF, Wang HX, Zhao HN, Tang JJ, Wu CJ, Lu LT, Liao WQ, Lu XC. Curcumin cytotoxicity is enhanced by PTEN disruption in colorectal cancer cells. World J Gastroenterol 2013; 19(40): 6814-6824
URL: https://www.wjgnet.com/1007-9327/full/v19/i40/6814.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i40.6814