Restrictive vs liberal transfusion for upper gastrointestinal bleeding: A meta-analysis of randomized controlled trials

Table 3 Baseline characteristics of patients in included studies

Ref.	Groups	No. Patients	Age (yr)	Sex (male:female)	Source of bleeding	Hematocrit atadmission	Hemoglobin atadmission (g/dL)
Blair et al[25]	Restrictive transfusion	26	60 ± 4.5	2:1	Gastric ulcer (n = 4); duodenal ulcer (n = 13); carcinoma (n = 2); Mallory-Weiss tear (n = 3); not visualized (n = 4)	29 ± 1.6	NA
	Liberal transfusion	24	64 ± 3.6	2:1	Gastric ulcer (n = 2); duodenal ulcer (n = 17); carcinoma (n = 1); Mallory-Weiss tear (n = 2); not visualized (n = 2)	28 ± 1.2	NA
Elizalde et al[24]	Restrictive transfusion	8	60 ± 4	5/3	Bleeding from esophageal varices (n = 7); bleeding from gastric varices in the fundus of the stomach (n = 1)	27.0 ± 1.3	91.5 ± 6.8
	Liberal transfusion	8	64 ± 2	4/4	Bleeding from esophageal varices (n = 7); bleeding from gastric varices in the fundus of the stomach (n = 1)	27.0 ± 1.3	90.5 ± 3.96
Villarejo et al[23]	Restrictive transfusion	14	56.8 ± 12.8	9/5	Mallory Weiss (n = 2); erosive gastritis (n = 14); erosive gastroduodenitis (n = 4); Forrest gastric ulcer (n = 10); Forrest duodenal ulcer (n = 10); erosive duodenitis (n = 1)	26.9 ± 4.29	8.76 ± 2.47
	Liberal transfusion	13	45.3 ± 14.6	9/4		28.3 ± 5.59	8.85 ± 2.53
Villanueva et al[14]	Restrictive transfusion	444	NA	NA	Peptic ulcer (n = 228); gastroesophageal varices (n = 101); Mallory-Weiss tears (n = 25); erosive gastritis or esophagitis (n = 38); neoplasms (n = 16); other (n = 36)	NA	9.6 ± 2.2
	Liberal transfusion	445	NA	NA	Peptic ulcer (n = 209); gastroesophageal varices (n = 109); Mallory-Weiss tears (n = 30); erosive gastritis or esophagitis (n = 29); neoplasms (n = 20); other (n = 48)	NA	9.4 ± 2.4