Abnormal DNA-PKcs and Ku 70/80 expression may promote malignant pathological processes in gastric carcinoma

Table 1 Differential immunohistochemical positive rate of DNA-dependent protein kinase and Ku 70/80 in gastric carcinoma and normal gastric mucosa tissues

Group	n	DNA-PKcs				P value	Ku 70/80				P value
		-	+	++	+++		-	+	++	+++
NGM	34	34	0	0	0	< 0.01	7	12	12	3	< 0.01
GC	146	9	24	65	48		5	19	50	72
H. pylori positive
NGM	16	16	0	0	0	< 0.01	2	4	8	2	< 0.10
GC	57	3	6	26	22		1	4	19	33
H. pylori negative
NGM	18	18	0	0	0	< 0.01	5	8	4	1	< 0.01
GC	89	6	18	39	26		4	15	31	39

H. pylori: Helicobacter pylori; GC: Gastric carcinoma; NGM: Normal gastric mucosa; DNA-PKcs: DNA-dependent protein kinase.