Risk of ileal pouch neoplasms in patients with familial adenomatous polyposis

Table 2 Summary of 21 cases of ileal pouch cancer in familial adenomatous polyposis

Ref.	Year	Sex	Operation	Type of pouch	Staging of initial surgery	Age of pouch (yr)	Shape	Size (mm)	Staging of pouch cancer	No. of pouch polyps	Time to cancer (yr)	Outcome	Interval since last endoscopy (yr)
Bassuini et al[40]	1996	M	IPAA	/handsewn	No cancer	28	Large polypoid	N	T3,N+	N	3	N	No follow-up
Palkar et al[41]	1997	F	IPAA	J-pouch handsewn	No cancer	39	Large polypoid	40 × 35	T4N0	Exist	4.7	Alive	0.3
Kim et al[42]	1997	N	N	N	N	N	N	N	N	N	N	N	N
Cherki et al[43]	2003	F	IPAA	J-pouch handsewn	TisN0M0	35	N	N	T3N1M1	N	3.5	Died	0.5
Linehan et al[44]	2007	M	IPAA	/double stapled	Dukes A	30	N	N	T3N0	N	9	Alive	No follow-up
Friederich et al[31]	2008	M	IPAA	/handsewn	No cancer	21.3	N	N	Dukes C	0	14	N	4.4
		M	IPAA	/stapled	No cancer	26.7	N	N	Dukes B	0	10	N	2.1
		M	IPAA	/handsewn	No cancer	16	N	N	Dukes B	N	16	N	No follow-up
		F	IPAA	/stapled	No cancer	29.6	N	N	Dukes B	exist	6	N	0.6
Tajika et al[45]	2009	F	IPAA	J-pouch/handsewn	TisN0M0	46	Type 2	30 × 25	T4N2M0	0	8.6	Died 3Y	0.75
		M	Kock	Kock/handsewn	No cancer	48	Type 1	40 × 35	T3N0M0	10 <	20	Died by U	No follow-up
Ault et al[46]	2009	M	IPAA	S-pouch/handsewn	Four cancer	61	ND	20-30	T2N1	N	11	Died by U	6
		F	IPAA	ND	No cancer	40	Type 1	N	N	N	13	meta	No follow-up
Lee et al[47]	2009	F	IPAA	J-pouch/	T2N0	56	Type 2	30 × 25	T3N2	0	7	meta 2Y	4
Banasiewicz et al[35]	2011	N	IPAA	J-pouch/	N	N	N	N	N	N	N	N	N
		N	IPAA	J-pouch/	N	N	N	N	N	N	N	N	N
		N	IPAA	J-pouch/	N	N	N	N	N	N	N	N	N
		N	IPAA	J-pouch/	N	N	N	N	N	N	N	N	N
Tonelli et al[36]	2012	M	IPAA	S-pouch/handsewn	No cancer	26	Type 2	20 <	T3N0M0	ND	3	Died 6 mo	1
		F	IPAA	S-pouch/handsewn	TisN0M0	47	IIa + IIc	N	T2N0M0	0	11	Alive at 56 mo	0.5
Makni et al[37]	2012	F	IPAA	J-pouch/	No cancer	26	N	20	N	Many	10	Died 1Y+	0.66

M: Male; F: Female; IPAA: Ileal pouch-anal anastomosis; Kock: Kock continent ileostomy; N: Not described; AV: Anal verge; U: Unrelated disease; Time to cancer: Interval between cancer diagnosis and pouch construction.