Increased expression of tyrosine phosphatase SHP-2 in Helicobacter pylori-infected gastric cancer

Table 3 Multivariate analyses for disease-specific survival

	RR (95% CI)	P value
SHP-2 expression
H-score (201-300) (n = 118)
H-score (100-200) (n = 115)	0.99 (0.63-1.56)	0.98
H-score (1-99) (n = 52)	1.08 (0.72-1.64)	0.70
Negative (0) (n = 20)	1.04 (0.49-1.67)	0.82
Tumor node metastasis staging
I (n = 25)
II (n = 51)	1.87 (0.52-6.79)	0.34
III (n = 195)	3.94 (1.22-12.74)	0.02
IV (n = 34)	13.63 (4.04-46.06)	0.00
Lymph-vascular invasion
Yes (n = 142)
No (n = 163)	1.61 (1.09-2.37)	0.02

Calculated by age, sex, differentiation, lymph-vascular invasion and tumor node metastasis staging adjusted Cox regression model. RR: Relative risk.