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©2013 Baishideng Publishing Group Co.
World J Gastroenterol. Jan 28, 2013; 19(4): 575-580
Published online Jan 28, 2013. doi: 10.3748/wjg.v19.i4.575
Published online Jan 28, 2013. doi: 10.3748/wjg.v19.i4.575
Table 2 SHP-2 expressions and clinical characteristics of 305 gastric cancer patients
| H-score, n (%) | Median H-score (quartile) | P value | ||||
| 0 | 1-99 | 100-200 | 201-300 | |||
| Sex | ||||||
| Male (n = 233) | 16 (6.9) | 44 (18.9) | 79 (33.9) | 94 (40.3) | 160 (100-240) | 0.82 |
| Female (n = 72) | 4 (5.6) | 8 (11.1) | 36 ( 50.0) | 24 (33.3) | 160 (140-240) | |
| Age | ||||||
| ≤ 60 yr (n = 129) | 9 (7.0) | 23 (17.8) | 50 (38.8) | 47 (36.4) | 160 (110-240) | 0.92 |
| > 60 yr (n = 176) | 11 (6.3) | 29 (16.5) | 65 (36.9) | 71 (40.3) | 180 (110-240) | |
| Differentiation | ||||||
| Well (n = 6) | 0 (0) | 1 (16.7) | 1 (16.7) | 4 (66.7) | 225 (155-270) | 0.43 |
| Moderate (n = 114) | 8 (7.0) | 20 (17.5) | 41 (36.0) | 45 (39.5) | 160 (115-240) | |
| Poor (n = 185) | 12 (6.5) | 31 (16.8) | 73 (39.5) | 69 (37.3) | 160 (120-240) | |
| Lymph-vascular invasion | ||||||
| No (n = 142) | 9 (6.3) | 22 (15.5) | 54 (38.0) | 57 (40.1) | 160 (120-240) | 0.89 |
| Yes (n = 163) | 11 (6.7) | 30 (18.4) | 61 (37.4) | 61 (37.4) | 160 (100-240) | |
| Nerve invasion | ||||||
| No (n = 184) | 14 (7.6) | 30 (16.3) | 70 (38.0) | 70 (38.0) | 160 (120-240) | 0.40 |
| Yes (n = 121) | 6 (5.0) | 22 (18.2) | 45 (37.2) | 48 (39.7) | 160 (120-240) | |
| TNM staging | ||||||
| I (n = 25) | 0 (0) | 3 (12.0) | 12 (48.0) | 10 (40.0) | 180 (140-270) | 0.34 |
| II (n = 50) | 4 (8.0) | 8 (16.0) | 13 (26.0) | 25 (50.0) | 195 (115-270) | |
| III (n = 194) | 14 (7.2) | 32 (16.5) | 77 (39.7) | 71 (36.6) | 160 (120-240) | |
| IV (n = 36) | 0 (0) | 7 (20.6) | 14 (41.2) | 13 (38.2) | 160 (100-242) | |
| Invasion | ||||||
| T1 (n = 9) | 0 (0) | 0 (0) | 4 (44.4) | 5 (55.6) | 240 (170-270) | 0.34 |
| T2 (n = 37) | 1 (2.7) | 7 (18.9) | 18 (48.6) | 11 (29.7) | 160 (120-225) | |
| T3 (n = 225) | 19 (8.4) | 38 (16.9) | 79 (35.1) | 89 (39.6) | 160 (100-240) | |
| T4 (n = 34) | 0 (0) | 7 (20.6) | 14 (41.2) | 13 (38.2) | 160 (120-248) | |
| Lymph node metastases | ||||||
| N0 (n = 66) | 3 (4.5) | 10 (15.2) | 23 (34.8) | 30 (45.5) | 180 (140-270) | 0.17 |
| N1 (n = 94) | 7 (7.4) | 15 (16.0) | 31 (33.0) | 41 (43.6) | 180 (120-240) | |
| N2 (n = 79) | 3 (3.8) | 15 (19.0) | 39 (49.4) | 22 (27.8) | 160 (120-210) | |
| N3 (n = 66) | 7 (10.6) | 12 (18.2) | 22 (33.3) | 25 (37.9) | 160 (100-270) | |
| Distant metastasis | ||||||
| No (n = 266) | 18 (6.8) | 43 (16.2) | 101(38.0) | 104 (39.1) | 170 (120-240) | 0.52 |
| Yes (n = 39) | 2 (5.1) | 9 (23.1) | 14 (35.9) | 14 (35.9) | 160 (100-240) | |
| Survival | ||||||
| Survived (n = 180) | 12 (6.7) | 28 (15.6) | 69 (38.3) | 71 (39.4) | 180 (120-240) | 0.77 |
| Died (n = 125) | 8 (6.4) | 24 (19.2) | 46 (36.8) | 47 (37.6) | 160 (100-240) | |
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Citation: Jiang J, Jin MS, Kong F, Wang YP, Jia ZF, Cao DH, Ma HX, Suo J, Cao XY. Increased expression of tyrosine phosphatase SHP-2 in
Helicobacter pylori -infected gastric cancer. World J Gastroenterol 2013; 19(4): 575-580 - URL: https://www.wjgnet.com/1007-9327/full/v19/i4/575.htm
- DOI: https://dx.doi.org/10.3748/wjg.v19.i4.575