Expression and significance of Musashi-1 in gastric cancer and precancerous lesions

Table 1 Expression intensity of Musashi-1 and proliferating cell nuclear antigen in different pathological tissues

Pathological tissues	Msi-1 protein staining intensity (n)				PCNA protein staining intensity (n)
	-	+	++	+++	-	+	++	+++
Normal gastric mucosa	17	19	0	0	27	9	0	0
Intestinal metaplasiaab	7	21	3	0	0	9	10	12
Low grade intraepithelial neoplasia	21	32	4	0	0	9	29	19
High grade intraepithelial neoplasia	19	17	4	1	0	6	16	19
Intestinal-type GCcd	12	29	9	4	0	0	10	44

^aP < 0.05,

^bP < 0.01, significantly different vs normal gastric mucosa;

^cP < 0.05,

^dP < 0.01, significantly different vs high-grade intraepithelial neoplasia. PCNA: Proliferating cell nuclear antigen; Msi-1: Musashi-1; GC: Gastric cancer.