Anisodamine accelerates spontaneous passage of single symptomatic bile duct stones ≤ 10 mm

Table 2 Rate of spontaneous passage of common bile duct stones

Diameter of CBD stone	Control group	Anisodamine group	P value
	(n = 97)	(n = 100)	(intergroup)
< 5 mm	31.8% (15/44)	71.1% (31/45)	0.001
≥ 5 mm and ≤ 10 mm	15.1% (7/53)	27.3% (16/55)	0.044
Total	22.7% (22/97)	47.0% (47/100)	0.000
Within-group P	0.014	0.000
Week 1	5.2% (5/97)	17.0% (17/100)	0.008
Week 2	5.4% (5/92)	28.9% (24/83)	0.000
Week 3	6.9% (6/87)	5.1% (3/59)ac	0.740
Week 4	7.4% (6/81)	5.4% (3/56)ac	0.737
Total	22.7% (22/97)	47.0% (47/100)	0.000
Within-group P	0.907	0

^aP < 0.05 vs week 1;

^cP < 0.05 vs week 2. CBD: Common bile duct.