HER2 in gastric cancer: Comparative analysis of three different antibodies using whole-tissue sections and tissue microarrays

doi:10.3748/wjg.v19.i38.6438

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Oct 14, 2013 (publication date) through Dec 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 14, 2013; 19(38): 6438-6446
Published online Oct 14, 2013. doi: 10.3748/wjg.v19.i38.6438

Table 6 Comparison of the areas under the receiver operating characteristic curve according to the type of sample (whole-tissue section and tissue microarray) and the antibodies

		Whole-tissue sections
			HercepTest	4B5	SP3
		AUC	0.73	0.91	0.78
TMAs	HercepTest	0.71	P = 0.572	P = 0.001	P = 0.013
	4B5	0.79	P = 0.289	P = 0.027	P = 0.201
	SP3	0.80	P = 0.265	P = 0.034	P = 0.244

AUC: Area under the receiver operating characteristic curve; TMA: Tissue microarray.

Citation: Abrahão-Machado LF, Jácome AADA, Wohnrath DR, Santos JSD, Carneseca EC, Fregnani JHTG, Scapulatempo-Neto C. HER2 in gastric cancer: Comparative analysis of three different antibodies using whole-tissue sections and tissue microarrays. World J Gastroenterol 2013; 19(38): 6438-6446
URL: https://www.wjgnet.com/1007-9327/full/v19/i38/6438.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i38.6438