Irritable bowel syndrome and organic diseases: A comparative analysis of esophageal motility

Table 3 Comparative manometric findings in patients with with irritable bowel syndrome, systemic lupus erythematosus and systemic sclerosis

	IBS	SLE	SSc	P value
Lower esophageal sphincter
Pressure (mmHg)	22 ± 5	28 ± 8.9	26 ± 5.2	P < 0.0512
Length (cm)	3.6 ± 1.3	3.4 ± 1.1	3.6 ± 1
Relaxation (%)	84.8 ± 15.4	89.5 ± 13.2	83.4 ± 10.4
Distal esophagus
Amplitude (mmHg)	103.6 ± 33.7	107.3 ± 53.3	43.3 ± 48.2	P < 0.00123
Duration (s)	4.3 ± 1.4	4.7 ± 1.4	2.9 ± 2.9
Velocity (cm/s)	3 ± 1.6	2.6 ± 1	1.4 ± 2	P < 0.0523
Middle esophagus
Amplitude (mmHg)	78.3 ± 35.7	75.9 ± 35	39.2 ± 42.4	P < 0.0123
Duration (s)	3.3 ± 1.3	3.4 ± 1.3	2.3 ± 2.2
Velocity (cm/s)	3.5 ± 1.4	3.9 ± 3.4	1.3 ± 3.7	P < 0.0523
Proximal esophagus
Amplitude (mmHg)	67.3 ± 23.3	50.6 ± 19.8	58.3 ± 15.9	P = 0.051
Duration (s)	2.5 ± 0.7	2.2 ± 0.7	2.8 ± 0.6
Velocity (cm/s)	2.5 ± 1.1	3.6 ± 2.3	3.0 ± 2.4
Upper esophageal sphincter
Pressure (mmHg)	70.5 ± 22.3	52.7 ± 20	50.2 ± 17.8	P < 0.0512
Length (cm)	3.6 ± 1.0	2.8 ± 1.0	2.7 ± 0.9	P < 0.0512
Relaxation (%)	94.7 ± 8.0	85.2 ± 12.7	87.1 ± 12

¹Between IBS and SLE;

²Between IBS and SSc;

³Between SLE and SSc. IBS: Irritable bowel syndrome; SLE: Systemic lupus erythematosus; SSc: Systemic sclerosis.