Lymph node metastasis in gastric cardiac adenocarcinoma in male patients

Table 7 Correlation between lymph node metastases at pN1, pN2 and pN3 and clinicopathological factors for sex difference

Clinicopathological factors	pN1			pN2			pN3
	Female LN+	Male LN+	P value	Female LN+	Male LN+	P value	Female LN+	Male LN+	P value
Age (yr)			0.179			0.692			0.159
< 60	5 (15.2)	28 (84.8)		2 (18.2)	9 (81.8)		0 (0.0)	4 (100.0)
≥ 60	19 (27.1)	51 (72.9)		3 (25.0)	9 (75.0)		4 (36.4)	7 (63.6)
Tumor size (cm)			0.792			0.692			0.475
< 2.0	0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)
2.0-5.0	15 (24.2)	47 (75.8)		2 (18.2)	9 (81.8)		1 (16.7)	5 (83.3)
> 5.0	9 (22.0)	32 (78.0)		3 (25.0)	9 (75.0)		3 (33.3)	6 (66.7)
Gross appearance			0.960			0.472			0.423
Type 0	0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)
Type 1	2 (40.0)	3 (60.0)		0 (0.0)	1 (100.0)		0 (0.0)	0 (0.0)
Type 2	19 (23.5)	62 (76.5)		4 (21.1)	15 (78.9)		3 (23.1)	10 (76.9)
Type 3	2 (20.0)	8 (80.0)		1 (50.0)	1 (50.0)		1 (50.0)	1 (50.0)
Type 4	1 (14.3)	6 (85.7)		0 (0.0)	1 (100.0)		0 (0.0)	0 (0.0)
Tumor differentiate			0.555			0.782			0.634
Differentiated	9 (20.5)	35 (79.5)		2 (25.0)	6 (75.0)		2 (33.3)	4 (66.7)
Undifferentiate	15 (25.4)	44 (74.6)		3 (20.0)	12 (80.0)		2 (22.2)	7 (77.8)
Pathological tumor depth			0.624			0.738
T1	0 (0.0)	1 (100.0)		0 (0.0)	0 (0.0)		0 (0.0)	0 (0.0)	NS
T2	2 (25.0)	6 (75.0)		0 (0.0)	1 (100.0)		0 (0.0)	0 (0.0)
T3	0 (0.0)	3 (100.0)		0 (0.0)	1 (100.0)		0 (0.0)	0 (0.0)
T4	22 (24.2)	69 (75.8)		5 (23.8)	16 (76.2)		4 (26.7)	11 (73.3)
Lymphatic invasion			0.744			0.567			0.634
Positive	5 (20.8)	19 (79.2)		1 (14.3)	6 (85.7)		2 (33.3)	4 (66.7)
Negative	19 (24.1)	60 (75.9)		4 (25.0)	12 (75.0)		2 (22.2)	7 (77.8)
Venous invasion			0.198			0.052			0.533
Positive	2 (50.0)	2 (50.0)		1 (100.0)	0 (0.0)		0 (0.0)	1 (100.0)
Negative	22 (22.2)	77 (77.8)		4 (18.2)	18 (81.8)		4 (28.6)	10 (71.4)
Nerve invasion			0.247			0.862			0.733
Positive	5 (35.7)	9 (64.3)		1 (25.0)	3 (75.0)		2 (33.3)	4 (66.7)
Negative	19 (21.6)	69 (78.4)		4 (21.1)	15 (78.9)		2 (25.0)	6 (75.0)
Esophageal involvement			0.321			0.435			0.930
Presence	4 (16.0)	21 (84.0)		0 (0.0)	2 (100.0)		1 (25.0)	3 (75.0)
Absence	20 (25.6)	58 (74.4)		5 (23.8)	16 (76.2)		3 (27.3)	8 (72.7)