Overexpression of insulin-like growth factor-I receptor as a pertinent biomarker for hepatocytes malignant transformation

Figure 2 Gene amplification, sequencing and homological analysis of liver insulin-like growth factor I receptor. A: The amplified fragments of rat insulin-like growth factor I receptor (IGF-IR) mRNA by reverse transcription-nested polymerase chain reaction 1, no positive fragments from control rat liver 2, the positive fragments from degeneration rat (Deg) liver; 3, the positive fragments from precancerous rat (Pre-C) liver, and 4, the positive fragments from hepatocellular carcinoma (HCC) rat liver; B: The amplified fragment of rat IGF-IR mRNA was confirmed by sequencing and alignment of nucleotide sequences from rat liver.