Overexpression of insulin-like growth factor-I receptor as a pertinent biomarker for hepatocytes malignant transformation

Figure 1 Rat livers and the histopathological alterations of rat tissues during malignant transformation of hepatocytes. A-C: The appearances of rat livers at different stages at early stage (A), at intermediate stage (B), and at later stage (C); D-F: The histopathology alteration (hematoxylin and eosin staining) of the corresponding rat liver section (× 200); G-I: The immunohistochemical confirmation of corresponding rat hepatic gamma-glutamyl transferase at the same stage (× 200).