Glycyrrhizinate reduces portal hypertension in isolated perfused rat livers with chronic hepatitis

Table 3 Pathological changes and inducible nitric oxide synthase levels (mean ± SE, n = 8)

Groups	PP (mmHg)	Lobule	Collagen	iNOS-OD/V
d00	6.648 ± 2.235	0.564% ± 0.022%	0.048% ± 0.013%	0.165 ± 0.011
d28	9.225 ± 2.114b	0.511% ± 0.031%b	0.248% ± 0.120%b	0.197 ± 0.005b
d56	24.724 ± 3.368bd	0.230% ± 0.024%bd	1.974% ± 0.637%bd	0.132 ± 0.010bd
d84	26.752 ± 3.263bdf	0.134% ± 0.009%bdf	5.925% ± 1.761%bdf	0.236 ± 0.040bdf

^bP < 0.01 vs d₀₀;

^dP < 0.01 vs d₂₈;

^fP < 0.01 vs d₅₆. PP: Portal pressure; iNOS: Inducible nitric oxide synthase.