Modulation of individual components of gastric motor response to duodenal glucose

Figure 2 Antral, isolated pyloric, duodenal pressure waves and pyloric tone at differing caloric loads. A: Reduction in antral motility occurred with increasing glucose load with marked attenuation of antral pressure wave activity at 1.5 kcal/min, when compared to 0 kcal/min (0 kcal/min: 7.5 ± 1.8 waves/20 min vs 1.5 kcal: 2.8 ± 1.3 waves/20 min; P = 0.007); B: The frequency of isolated pyloric pressure waves increased with increasing caloric load. The number of waves/20 min were statistically different between 0 and 1.0 kcal/min (0 kcal/min: 8.0 ± 2.3 waves/20 min vs 1.0 kcal/min: 25.9 ± 3.7 waves/20 min; P = 0.002); C: The nutrient load did not effect duodenal wave frequency when comparing 0 kcal/min to 1.5 kcal/min (0 kcal/min: 24.4 ± 4.7 waves/20 min vs 1.5 kcal/min: 34.7 ± 4.9 waves/20 min; P = 0.22); D: Pyloric tone increased in response to increasing caloric loads (P = 0.015). Between 0.5 and 1.5 kcal/min the difference was significant (0.5 kcal/min: -0.4 ± 1.1 mmHg vs 1.5 kcal/min: 3.1 ± 1.3 mmHg; P = 0.008).