Aberrant TGF-β1 signaling contributes to the development of primary biliary cirrhosis in murine model

Figure 4 Immunoblot of transforming growth factor-β1, transforming growth factor-β receptor I, transforming growth factor-β receptor II, p-Smad2/3, α-smooth muscle actin antibody and α1 (I) collagen. A: Western blotting analyses of transforming growth factor (TGF)-β1, TGF-β receptor I (TβRI), TβRII, pSmad2/3, α-smooth muscle actin (SMA) antibody and α1 (I) collagen expression of the liver homogenates. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) was an internal control for equal loading (n = 6); B: ^aP < 0.05, ^bP < 0.01 vs control mice.