Association between vitamin D and hepatitis C virus infection: A meta-analysis

Table 2 Summary of included studies regarding vitamin D and hepatitis C virus aspects

Study	Sample size	HCV genotype	Mean viral load log, (UI/mL, average)	SVR (n)	SVR1 (above/below 30 ng/mL)	Previous HCV treatment
Nimer et al[26]	50 HCV infected individuals	II:28	NA	Treated: 19/20	19/23	None
		III:22		Non treated: 23/30
Milazzo et al[25]	93 HIV/HCV infected individuals	I:66	5.8 (5.3-6.2)	21	7/14	Naïve: 31
		Non I:27				Non responder or relapser to a previous anti-HCV therapy: 20
Abou-Mouch et al[27]	72 HCV infected individuals	I:72	NA	Treated: 31	31/15	None
				Non treated: 15
Bitetto et al[20]	42 HCV infected individuals	I:32	Treated: 5 (3-7)	Treated: 8/15	6/7	All
		Non I:10	Non treated: 5 (3-7)	Non treated: 5/27
Soumekh et al[28]	88 HIV/HCV infected individuals	I or IV:77	NA	13	6/7	All
		Non I:11
Reiberg et al[29]	84 HIV/HCV infected individuals	I:47	4.5 (1.4-7.6)	39	11/28	None
		Non I:37
Jazwinski et al[23]	82 HCV infected individuals	I:82	NA	74	39/35	None
Lange et al[18]	468 HCV infected individuals	I:317	5.9 (2.3-7.7)	280	17/152	None
		I:43
		I:108
Terrier et al[22]	189 HIV/HCV infected individuals	I:84	5.9 (0-7)	61	9/52	None
		II or III:73
		IV:31
		Other 1
Bitetto et al[21]	211 HCV individuals	I:95	5 (2-7)	134	78/56	None
		II:63
		II:38
		IV-V:15
Petta et al[17]	196 HCV infected individuals	I:196	5 (2-8)	82	26/56	None

¹According to basal vitamin D cut-off or supplementation. NA: Not available as mean value; HCV: Hepatitis C virus; HIV: Human immunodeficiency virus; SVR: Sustained virological response.