Association between UCP3 gene polymorphisms and nonalcoholic fatty liver disease in Chinese children

Table 1 Demographic and biochemical features of patients with nonalcoholic fatty liver disease and normal controls

	NAFLD	Controls	P value
	(n = 250)	(n = 200)
Gender (M/F)	147/103	109/91	0.36
Age (yr)	10.78 ± 2.07	10.63 ± 2.22	0.47
Body height (cm)	148.28 ± 11.77	141.22 ± 12.91	0.00
Body weight (kg)	62.82 ± 15.17	34.72 ± 10.28	0.00
BMI (kg/m2)	28.13 ± 3.50	17.05 ± 2.16	0.00
SBP (mmHg)	114.02 ± 11.55	91.61 ± 9.68	0.00
DBP (mmHg)	68.57 ± 8.63	66.43 ± 7.67	0.01
Waist (cm)	89.84 ± 9.74	58.07 ± 7.04	0.00
Hip (cm)	93.85 ± 8.66	70.09 ± 7.85	0.00
WHR	0.95 ± 0.06	0.83 ± 0.05	0.00
FBG (mmol/L)	4.99 ± 0.41	4.91 ± 0.38	0.04
TCHO (mmol/L)	4.40 ± 0.89	4.14 ± 0.66	0.00
HDLc (mmol/L)	1.33 ± 0.51	1.52 ± 0.30	0.00
LDLc (mmol/L)	2.53 ± 0.72	2.19 ± 0.56	0.00
TG (mmol/L)	1.41 ± 0.84	0.80 ± 0.31	0.00
ALT (mmol/L)	72.70 ± 70.16	17.14 ± 10.48	0.00
AST (mmol/L)	47.26 ± 36.61	25.22 ± 6.53	0.00
FIN (mIU/L)	20.49 ± 17.25	6.98 ± 3.59	0.00
HOMA-IR	4.57 ± 3.92	1.52 ± 0.78	0.00

Data are expressed as absolute mean ± SD. Analysis was conducted using χ² test and t test. NAFLD: Nonalcoholic fatty liver disease; BMI: Body mass index; SBP: Systolic blood pressure; DBP: Diastolic pressure; WHR: Waist-to-hip ratio; FBG: Fasting blood glucose; TCHO: Total cholesterol; HDLc: High-density lipoprotein-cholesterol; LDLc: Low-density lipoprotein-cholesterol; TG: Total triglyceride; ALT: Alanine transaminase; AST: Aspartate aminotransferase; FIN: Fasting insulin; HOMA-IR: Homeostasis model assessment-estimated insulin resistance; M: Male; F: Female.