Erosive esophagitis associated with metabolic syndrome, impaired liver function, and dyslipidemia

Table 2 Logistic regression analysis of risk factors for erosive esophagitis

	Univariate analysis OR (95%CI)	P value	Multivariate analysis OR (95%CI)	P value
Obesity1	1.72 (1.10-1.80)	< 0.05		0.606
Central obesity2	1.60 (1.20-2.14)	< 0.05	1.38 (1.00-1.86)	< 0.05
Hypertension	1.43 (1.11-1.86)	< 0.05	1.35 (1.04-1.76)	< 0.05
Hyperglycemia	1.39 (1.07-1.80)	< 0.05		0.143
Hypertriglyceridemia	1.50 (1.15-1.95)	< 0.05	1.34 (1.02-1.76)	< 0.05
Low HDL-C	1.24 (0.91-1.67)	0.192	-	-
TC/HDL-C > 5	1.57 (1.17-2.12)	< 0.05	1.45 (1.06-1.97)	< 0.05
AST > 37 (U/L)	1.67 (1.14-2.45)	< 0.05	1.59 (1.08-2.34)	< 0.05
ALT > 40 (U/L)	1.40 (1.04-1.90)	< 0.05		0.986

¹Defined as body mass index ≥ 25 kg/m²;

²Defined as waist circumference ≥ 90 cm for men and ≥ 80 cm for women. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; HDL-C: High-density lipoprotein cholesterol; TC: Total cholesterol.