ITGA1 polymorphisms and haplotypes are associated with gastric cancer risk in a Korean population

doi:10.3748/wjg.v19.i35.5870

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World Journal of Gastroenterology

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1007-9327

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World J Gastroenterol. Sep 21, 2013; 19(35): 5870-5876
Published online Sep 21, 2013. doi: 10.3748/wjg.v19.i35.5870

Table 2 Frequency of ITGA1 polymorphisms in cases and controls

SNP	Chromosomal position	Amino acid change	Genotype case/control				Case		Control
SNP	Chromosomal position	Amino acid change	Genotype case/control				Frequency	HWE¹	Frequency	HWE¹
rs13188662	2686006	-	AA	AG	GG	N	0.280	0.573	0.276	0.597
rs13188662	2686006	-	249/253	186/186	40/38	475/477	0.280	0.573	0.276	0.597
rs11740785	2707341	-	AA	AC	CC	N	0.241	0.866	0.229	0.259
rs11740785	2707341	-	279/290	166/156	32/31	477/477	0.241	0.866	0.229	0.259
rs1820167	2713715	-	AA	AG	GG	N	0.435	0.806	0.420	0.904
rs1820167	2713715	-	151/162	237/229	89/83	477/477	0.435	0.806	0.420	0.904
rs1862610	2722239	-	CC	AC	AA	N	0.369	0.861	0.387	0.484
rs1862610	2722239	-	172/205	223/192	82/80	477/477	0.369	0.861	0.387	0.484
rs2432143	2725674	-	TT	TC	CC	N	0.104	0.671	0.146	0.658
rs2432143	2725674	-	382/346	87/121	8/10	477/477	0.104	0.671	0.146	0.658
rs2447867	2751733	C/C	CC	TC	TT	N	0.490	0.742	0.430	0.769
rs2447867	2751733	C/C	123/155	241/229	113/89	477/473	0.490	0.742	0.430	0.769
rs4865745	2770258	-	TT	TC	CC	N	0.270	0.892	0.268	0.124
rs4865745	2770258	-	253/247	186/198	35/28	474/473	0.270	0.892	0.268	0.124
rs13163497	2773367	-	GG	AG	AA	N	0.110	0.409	0.108	0.515
rs13163497	2773367	-	375/381	97/89	4/7	476/477	0.110	0.409	0.108	0.515
rs1904163	2780355	-	CC	TC	TT	N	0.298	0.196	0.272	0.698
rs1904163	2780355	-	238/245	184/187	48/33	470/465	0.298	0.196	0.272	0.698
rs1466445	2789486	-	CC	TC	TT	N	0.460	0.783	0.455	0.696
rs1466445	2789486	-	139/142	233/229	101/100	473/471	0.460	0.783	0.455	0.696
rs16880453	2789866	-	GG	GC	CC	N	0.466	0.914	0.465	0.424
rs16880453	2789866	-	133/130	235/243	100/98	468/471	0.466	0.914	0.465	0.424
rs2452864	2796757	-	TT	TC	CC	N	0.367	0.874	0.369	0.368
rs2452864	2796757	-	190/183	224/230	63/59	477/472	0.367	0.874	0.369	0.368
rs1275659	2828018	-	AA	AG	GG	N	0.257	0.185	0.278	0.864
rs1275659	2828018	-	256/247	192/189	26/37	474/473	0.257	0.185	0.278	0.864
rs1871186	2828974	-	TT	TC	CC	N	0.221	0.723	0.213	0.674
rs1871186	2828974	-	287/296	166/157	22/23	475/476	0.221	0.723	0.213	0.674
rs988574	2835169	E/G	TT	TC	CC	N	0.180	0.723	0.183	0.674
rs988574	2835169	E/G	319/309	141/155	15/9	475/473	0.180	0.723	0.183	0.674

¹P value for deviation from Hardy-Weinberg Equilibrium (HWE). SNP: Single nucleotide polymorphism.

Citation: Yim DH, Zhang YW, Eom SY, Moon SI, Yun HY, Song YJ, Youn SJ, Hyun T, Park JS, Kim BS, Lee JY, Kim YD, Kim H. ITGA1 polymorphisms and haplotypes are associated with gastric cancer risk in a Korean population. World J Gastroenterol 2013; 19(35): 5870-5876
URL: https://www.wjgnet.com/1007-9327/full/v19/i35/5870.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i35.5870