Molecular epidemiology and putative origin of hepatitis C virus in random volunteers from Argentina

doi:10.3748/wjg.v19.i35.5813

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2013; 19(35): 5813-5827
Published online Sep 21, 2013. doi: 10.3748/wjg.v19.i35.5813

Table 3 Genetic divergence (DNASP software)

	Argentine general population sequences	GB deposited sequences from Argentina	Closest GB deposited sequences
HCV-1a
Argentine general population sequences	0.034
GB deposited sequences from Argentina	0.042	0.040
Closest GB deposited sequences	0.034	0.037	0.032
HCV-1b
Argentine general population sequences	0.082
GB deposited sequences from Argentina	0.074	0.046
Closest GB deposited sequences	0.054	0.050	0.045
HCV-2c
Argentine general population sequences	0.087
GenBank deposited sequences from Argentina	0.092	0.098
Closest GB deposited sequences	0.076	0.080	0.076

Hepatitis C virus (HCV)-1b (Argentine general population sequences): 0.082 vs 0.054, P < 0.001; 0.082 vs 0.074, P > 0.05; HCV-1b [GenBank (GB) deposited sequences from Argentina]: 0.046 vs 0.050, P < 0.001; HCV-2c (Argentine general population sequences): 0.087 vs 0.076, P < 0.001; 0.087 vs 0.092, P > 0.05; HCV-2c (GB deposited sequences from Argentina): 0.098 vs 0.08, P < 0.001. All P (HCV-1a) > 0.05. Genetic divergence (DNASP software), considering three separate HCV groups: our Argentine general population (sequenced in this study), Argentinian sequences already deposited in GB, and the closest GB worldwide sequences. All values obtained were statistically paired and compared by using the χ² test with Yates’ correction.

Citation: del Pino N, Oubiña JR, Rodríguez-Frías F, Esteban JI, Buti M, Otero T, Gregori J, García-Cehic D, Camos S, Cubero M, Casillas R, Guàrdia J, Esteban R, Quer J. Molecular epidemiology and putative origin of hepatitis C virus in random volunteers from Argentina. World J Gastroenterol 2013; 19(35): 5813-5827
URL: https://www.wjgnet.com/1007-9327/full/v19/i35/5813.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i35.5813