Criteria for the diagnosis and severity stratification of acute pancreatitis

Table 1 Laboratory/clinical criteria for grading the severity of acute pancreatitis

No.	Laboratory/clinical criteria
1	Base excess ≤ -3 mEq/L or shock (systolic blood pressure ≤ 80 mmHg)
2	PaO2 ≤ 60 mmHg (room air) or respiratory failure (artificial respiratory ventilation)
3	BUN ≥ 40 mg/dL or creatininee ≥ 2.0 mg/dL or oliguria (urinary volume ≤ 400 mL/d after hydration)
4	LDH: More than twice higher than the upper limit of normal (≥ 700 IU/L)
5	Serum total Ca ≤ 7.5 mg/dL
6	Platelet count ≤ 1 × 105/mm3
7	CRP ≥ 15 mg/dL
8	Positive score of SIRS criteria ≥ 3
9	Age ≥ 70 yr

One point for each positive factor. Severe acute pancreatitis: total scores ≥ 3 points. BUN: Blood urea nitrogen; LDH: Lactate dehydrogenase; SIRS: Systemic inflammatory response syndrome; CRP: C-reactive protein.