Pathophysiology, epidemiology, classification and treatment options for polycystic liver diseases

doi:10.3748/wjg.v19.i35.5775

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 21, 2013; 19(35): 5775-5786
Published online Sep 21, 2013. doi: 10.3748/wjg.v19.i35.5775

Table 1 Comparative epidemiological and genetic mutation characteristics of autosomal dominant polycystic kidney disease associated polycystic liver disease and isolated polycystic liver disease

Characteristics	ADPKD associated PLD	Isolated PLD
Prevalence	0.20%	< 0.01%
Type of inheritance	AD	AD
Gene mutated	PKD1; PKD2	PRKCSH; SEC63
Encoded product	Polycystin-1; Polycystin-2	Hepatocystin; Sec63 protein
Chromosome locus	216p13.3; 4q21	19p13.2; 6q21

AD: Autosomal dominant; ADPKD: Autosomal dominant polycystic kidney disease; PLD: Polycystic liver disease.

Citation: Abu-Wasel B, Walsh C, Keough V, Molinari M. Pathophysiology, epidemiology, classification and treatment options for polycystic liver diseases. World J Gastroenterol 2013; 19(35): 5775-5786
URL: https://www.wjgnet.com/1007-9327/full/v19/i35/5775.htm
DOI: https://dx.doi.org/10.3748/wjg.v19.i35.5775