Chronological changes in the liver after temporary partial portal venous occlusion

Figure 4 Changes in hepatic histology. Histology in temporary occluded lobes. A: 24 h occlusion, × 100; B: 36 h occlusion, × 400; C: In non-occluded lobes 24 h occlusion, × 100; D: 48 h occlusion, × 400 is shown by HE staining. In the occluded liver lobe, before reperfusion, coagulative necrosis may be observed around the central vein in proportion to the occlusion time. However, the above-mentioned necrotic area decreased at 48 h after portal vein reperfusion. In the non-occluded liver lobe, hepatocytes became hypertrophic, and some mitoses could be observed (arrows).