Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats

Figure 4 Effect of naringenin on tumor necrosis factor-α (A), interleukin-1β (B), interleukin-6 (C), prostaglandin E₂ (D) and nitric oxide (E) levels in colonic tissue of rats with acetic acid-induced ulcerative colitis (n = 6). Values are expressed as mean ± SE and analyzed using one way analysis of variance followed by Newman-Keuls post hoc test. ^bP < 0.01 control vs AA; ^cP < 0.05, ^dP < 0.01 AA vs NG25 + AA, NG50 + AA, NG100 + AA or MES + AA groups. TNF-α: Tumor necrosis factor-α; IL-1β: Interleukin-1β; IL-6: Interleukin-6; PGE₂: Prostaglandin E₂; AA: Acetic acid; NG: Naringenin; MES: Mesalazine.